The two main activities of the Spoke 8 of ICSC are related to medical research, which relies on supercomputing for the so-called In Silico Medicine and for the elaboration of large amounts of data produced by experimentation in the field of omic sciences (genomics, lipidomics, transcriptomics, etc.). More specifically, the goals of this Spoke are planning new clinical tests via simulation methods (in order to cut the time and costs of clinical trials), as well as the development of a technological platform that enables big data analysis through algorithms of artificial intelligence and machine learning. These studies will increase understanding of countless diseases, their diagnosis and prognosis, not to mention enable the development of new personalised drug treatments.  

Beyond the state of the art of reverse vaccinology: predicting vaccine efficacy with the universal immune system simulator for influenza